题名

急性胰臟炎病人的營養照護

DOI

10.6666/ClinMed.202202_89(2).0015

作者

楊筑穎;邱哲琳;楊妹鳳

关键词

急性胰臟炎(acute pancreatitis) ; 營養不良(malnutrition) ; 營養支持(nutrition support) ; 麩醯胺酸(glutamine)

期刊名称

臨床醫學月刊

卷期/出版年月

89卷2期(2022 / 02 / 25)

页次

84 - 88

内容语文

繁體中文

中文摘要

急性胰臟炎患者普遍存在營養不良的風險,而營養不良會增加併發症、死亡率與住院天數,因此每位急性胰臟炎患者應進行營養篩檢,對營養不良或有風險者即早進行營養介入。在熱量建議部分,輕度患者每天每公斤體重25-30大卡,中、重度患者每天每公斤體重30-35大卡;蛋白質建議量為每天每公斤體重1.2-1.5公克。當出現微量營養素缺乏症狀時,應進行補充。對於重度急性胰臟炎且只使用靜脈營養患者,建議靜脈給予麩醯胺酸每天每公斤體重0.2公克,以減少死亡率及感染相關併發症。積極營養介入可減少疾病相關併發症、死亡率及住院天數,並提升病人的生活品質。

主题分类 醫藥衛生 > 基礎醫學
醫藥衛生 > 社會醫學
参考文献
  1. Akyol, S,Mas, MR,Comert, B(2003).The effect of antibiotic and probiotic combination therapy on secondary pancreatic infections and oxidative stress parameters in experimental acute necrotizing pancreatitis.Pancreas,26,363-367.
  2. Arvanitakis, M,Ockenga, J,Bezmarevic, M(2020).ESPEN guideline on clinical nutrition in acute and chronic pancreatitis.Clin Nutr,39,612-631.
  3. Asrani, V,Chang, WK,Dong, Z(2013).Glutamine supplementation in acute pancreatitis: A metaanalysis of randomized controlled trials.Pancreatology,13,468-474.
  4. Butturini, G,Salvia, R,Bettini, R(2001).Infection prevention in necrotizing pancreatitis: an old challenge with new perspectives.J Hosp Infect,49,4-8.
  5. De, Waele, B,Vierendeels, T,Willems, G(1992).Vitamin status in patients with acute pancreatitis.Clin Nutr,11,83-86.
  6. Endo, A,Shiraishi, A,Fushimi, K(2018).Comparative effectiveness of elemental formula in the early enteral nutrition management of acute pancreatitis: a retrospective cohort study.Ann Intensive Care,8,69.
  7. Gramlich, L,Taft, AK(2007).Acute pancreatitis: practical considerations in nutrition support.Curr Gastroenterol Rep,9,323-328.
  8. Hall, JC,Heel, K,McCauley, R(1996).Glutamine.Br J Surg,83,305-312.
  9. Hollemans, RA,Hallensleben, NDL,Mager, DJ(2018).Pancreatic exocrine insufficiency following acute pancreatitis: Systematic review and study level meta-analysis.Pancreatology,18,253-262.
  10. Jacobson, BC,Vander, vliet, MB,Hughes, MD(2007).A prospective, randomized trial of clear liquids versus low-fat solid diet as the initial meal in mild acute pancreatitis.Clin Gastroenterol Hepatol,5,946-951.
  11. Kanthasamy, KA,Akshintala, VS,Singh, VK(2021).Nutritional Management of Acute Pancreatitis.Gastroenterol Clin North Am,50,141-150.
  12. Krueger, K,McClave, SA,Martindale, RG(2017).Pancreatitis.The ASPEN Adult Nutrition Support Core Curriculum,the United States:
  13. Li, JY,Yu, T,Chen, GC(2013).Enteral nutrition within 48 hours of admission improves clinical outcomes of acute pancreatitis by reducing complications: a meta-analysis.PLoS One,8,e64926.
  14. Lugli, AK,Carli, F,Wykes, L(2007).The importance of nutrition status assessment: the case of severe acute pancreatitis.Nutr Rev,65,329-334.
  15. Moraes, JM,Felga, GE,Chebli, LA(2010).A full solid diet as the initial meal in mild acute pancreatitis is safe and result in a shorter length of hospitalization: results from a prospective, randomized, controlled, double-blind clinical trial.J Clin Gastroenterol,44,517-522.
  16. Renner, IG,Savage, WT,Pantoja, JL(1985).Death due to acute pancreatitis. A retrospective analysis of 405 autopsy cases.Dig Dis Sci,30,1005-1018.
  17. Roberts, KM,Nahikian-Nelms, M,Ukleja, A(2018).Nutritional Aspects of Acute Pancreatitis.Gastroenterol Clin North Am,47,77-94.
  18. Scolapio, JS,Malhi-Chowla, N,Ukleja, A(1999).Nutrition supplementation in patients with acute and chronic pancreatitis.Gastroenterol Clin North Am,28,695-707.
  19. Singer, P,Blaser, AR,Berger, MM(2019).ESPEN guideline on clinical nutrition in the intensive care unit.Clin Nutr,38,48-79.
  20. Song, J,Zhong, Y,Lu, X(2018).Enteral nutrition provided within 48 hours after admission in severe acute pancreatitis: A systematic review and meta- analysis.Medicine,97,e11871.
  21. SunS,Yang, K,He, X(2009).Probiotics in patients with severe acute pancreatitis: A meta-analysis.Langenbecks Arch. Surg,394,171-177.
  22. Tenner, S,Baillie, J,DeWitt, J(2013).American College of Gastroenterology. American College of Gastroenterology guideline: management of acute pancreatitis.Am J Gastroenterol,108,1400-1416.
  23. Tenner, S,Steinberg, WM(2016).Acute Pancreatitis.Sleisenger and Fordtran’s gastrointestinal and liver disease,Philadelphia:
  24. Toouli, J,Biankin, AV,Oliver, MR(2010).Australasian Pancreatic Club. Management of pancreatic exocrine insufficiency: Australasian Pancreatic Club recommendations.Med J Aust,193,461-467.
  25. van Minnen, LP,Timmerman, HM,Lutgendorff, F(2007).Modification of intestinal flora with multispecies probiotics reduces bacterial translocation and improves clinical course in a rat model of acute pancreatitis.Surgery,141,470-480.
  26. Yao, H,He, C,Deng, L(2018).Enteral versus parenteral nutrition in critically ill patients with severe pancreatitis: a meta-analysis.Eur J Clin Nutr,72,66-68.
  27. Zhao, XL,Zhu, SF,Xue, GJ(2015).Early oral refeeding based on hunger in moderate and severe acute pancreatitis: a prospective controlled, randomized clinical trial.Nutrition,31,171-175.
  28. 潘之瑩,李嘉龍,吳啓華(2013)。急性胰臟炎的診斷與治療之最新進展。內科學誌,24,162-180。