針灸緩解大腸癌第四期化療後腹脹、腹痛－病例報告

Acupuncture Relieving Abdominal Distension and Abdominal Pain after Chemotherapy of Stage IV Colon Cancer: A Case Report

10.6718/TJCM.202103_27(1).0010

林庭安(Ting-An Lin)；崔皓鈞(Hao-Chun Tsui)；黃中瑀(Chung-Yu Huang)

第四期大腸癌 ； 腹腔溫熱化學療法 ； 化學治療 ； 標靶治療 ； 針灸 ； Stage IV Colon Cancer ； Hyperthermic intraperitoneal chemotherapy (HIPEC) ； Chemotherapy ； Targeted therapy ； Acupuncture

台北市中醫醫學雜誌

27卷1期（2021 / 03 / 30）

79 - 86

繁體中文

多年來結腸直腸癌高踞臺灣癌症死亡率第三名，雖然近年大腸直腸癌的治療不斷進步，但其治療副作用深深困擾病患。本病例報告為38歲第四期大腸癌合併腹膜及肝臟轉移患者，由於無法以手術切除腫瘤，接受腹膜溫熱化學治療（hyperthermic intraperitoneal chemotherapy, HIPEC）、FOLFIRI化學治療（Folinic acid, 5-FU, Irinotecan）及Cetuximab標靶治療後，出現腸阻塞的治療副作用，嚴重影響生活品質，轉而接受中醫輔助治療。患者接受針刺足三里、上巨虛及下巨虛後，其消化道症狀及生活品質獲得改善。希望經由本病例說明針灸緩解第四期大腸癌治療後副作用之臨床療效。

Colorectal cancer ranks third in cancer mortality in Taiwan. Although the treatment of colorectal cancer has been improved, the side effects have deeply troubled patients. This case is a 38-year-old male with stage IV colon cancer with peritoneal and liver metastases. Since the tumor cannot be surgically removed, he received hyperthermic intraperitoneal chemotherapy (HIPEC), FOLFIRI chemotherapy (Folinic acid, 5-FU, Irinotecan) and Cetuximab for targeted therapy. After above therapies, intestinal obstruction occurred seriously affected the quality of life. So he asked for acupuncture. After receiving acupuncture at Zusanli, Shangjuxu and Xiajuxu, his digestive symptoms and quality of life improved. We demonstrate that acupuncture can alleviate the side effects after the treatment of stage IV colon cancer.

1. (2013).Systematic Review of Acupuncture in Cancer Care: A Synthesis of the Evidence.J Clin Oncol,31(7),952-960.
2. (2016).Complications of Cytoreductive Surgery and HIPEC in the Treatment of Peritoneal Metastases.Indian J Surg Oncol,7(2),225-229.
3. (2020).Clinical Evidence for Association of Acupuncture and Acupressure With Improved Cancer Pain A Systematic Review and Meta-Analysis.JAMA Oncol.,6(2),271-278.
4. (2009).Laparoscopic Hyperthermic Intraperitoneal Peroperative Chemotherapy (HIPEC) in the Management of Refractory Malignant Ascites: A Multi-Institutional Retrospective Analysis in 52 Patients.Journal of Surgical Oncology,100,331-334.
5. (2018).Acupuncture and Related Therapies for Treatment of Postoperative Ileus in Colorectal Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Evid Based Complement Alternat Med
6. (2013).Malignant ascites: pathophysiology and treatment.Int J Clin Oncol,18,1-9.
7. (2021).Management of pain in colorectal cancer patients.Critical Reviews in Oncology/Hematology,157
8. 王丹華,王昌明,史永奮(2003)。下合穴為主治療腸梗阻 46 例。中國針灸，23(01)，12。
9. 陳長安(2017).常用藥物治療手冊.臺北市:全國藥品年鑑雜誌社.
10. 程凱,秦卓,王婧,翟麗靜(2015)。關於足三里、上巨虛、下巨虛的下合順序與主治特異性思考。中國針灸，35(11)，1167-1170。