癌因性疲憊中醫治療文獻綜論

A review of the literature on traditional Chinese medicine treatment of cancer-related fatigue

10.6718/TJCM.202403_30(1).0007

許哲維(Je-Wei Hsu)；楊仁鄰(Jen-Lin Yang)

癌因性疲憊 ； 中藥 ； 綜論

台北市中醫醫學雜誌

30卷1期（2024 / 03 / 17）

57 - 70

繁體中文;英文

大約三分之一接受癌症治療的患者，會在治療後數年內經歷癌因性疲憊（Cancer-related fatigue，CRF），本文彙整了評估CRF的量表工具，其中以MFI（Multidimensional Fatigue Inventory）最為推薦。癌因性疲憊於簡短疲勞量表評分超過4分時即會介入症狀治療。中醫病因病機以氣血兩虛論述最多，各家不同治法的辨證論治、治則中多強調補氣，經實證醫學驗證的藥物包括人參、西洋參、黃耆、黃精、補中益氣湯，多項臨床試驗研究已驗證其療效，其中黃耆注射液在台灣經過三期臨床試驗療效甚佳。

Approximately one-third of patients treated for cancer will suffer Cancer-related Fatigue (CRF) within several years after treatment. This article summarizes the assessment tools for CRF, with the Multidimensional Fatigue Inventory (MFI) being recommended. CRF, with a score of over 4 on the Brief Fatigue Inventory (BFI), warrants intervention for symptom management. In Traditional Chinese Medicine (TCM), the pathogenesis of CRF mainly involves deficiency of both Qi and Blood. Various schools of thought in TCM propose different treatment methods, mostly emphasizing Qi supplementation. Validated empirical medications include Ginseng, Astragalus, Polygonatum and Bu-Zhong-Yi-Qi-Tang. Several clinical trials have been conducted,among which Astragalus injection has shown excellent efficacy in Taiwan through three-phaseclinical trials.