题名

Triterpenes from Kadsura coccinea

作者

Hai-Xia Li；Jie Fan；Wen Hu；Chao Wang；Susumu Kitanaka；He-Ran Li

关键词

Kadsura coccinea ； Triterpene ； NO production inhibitory activities

期刊名称

Journal of Traditional and Complementary Medicine

卷期/出版年月

2卷2期（2012 / 04 / 01）

页次

154 - 157

内容语文

英文
中文摘要

In vitro anti-allergic screening of medicinal herbal extracts revealed that the 80% acetone extract of the rhizome of Kadsura coccinea inhibited nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ (IFN-γ) activated murine macrophage like cell line, RAW264.7. Further fractionation of the EtOAc extract led to the isolation of one new 3,4-seco-lanostane type triterpene named kadsuracoccin acid A (1) together with two known triterpenes anwuweizonic acid (2) and neokadsuranic acid B (3). Compounds 1-3 did not exhibit any inhibitory activities for NO production and IFN-γ activation.
主题分类 醫藥衛生 > 中醫藥學
参考文献
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