Exploratory Study on the Ayurvedic Therapeutic Management of Cerebral Palsy in Children at a Tertiary Care Hospital of Karnataka, India

10.4103/2225-4110.124345

Shailaja U；Prasanna N. Rao；Parikshit Debnath；Anjan Adhikari

Abhyanga ； Baladi Yoga ； Cerebral palsy ； Moorchita Tila Taila ； Mustadi Rajayapana Basti ； Shastikashali Pinda Sveda

Journal of Traditional and Complementary Medicine

4卷1期（2014 / 01 / 01）

49 - 55

英文

Cerebral palsy (CP) is the leading cause of childhood disability affecting cognitive function and developments in approximately 1.5 to 3 cases per 1000 live births. Based on Ayurvedic therapeutic principles, CP patients were subjected to Abhyanga (massage) with Moorchita Tila Taila (processed sesame oil) and Svedana (fomentation) with Shastikashali Pinda Sveda (fomentation with bolus of drugs prepared with boiled rice). Study group received Mustadi Rajayapana Basti (enema with herbal decoction) and Baladi Yoga (a poly-herbo-mineral formulation), while the placebo group received Godhuma Vati (tablet prepared with wheat powder) and saline water as enema. Treatment with Mustadi Rajayapana Basti and Baladi Yoga improved the activities of daily life by 8.79%, gross motor functions by 19.76%, and fine motor functions 15.05%, and mental functions like memory retention got improved by 15.43%. The placebo group showed an improvement of 0.21% in daily life activities, 2.8% in gross motor, and 2.4% in fine motor functions. Mustadi Rajayapana Basti and Baladi Yoga proved to be more supportive in improving the motor activities and gross behavioral pattern. Further clinical trials are required to evaluate and validate the maximum effect of the combination therapy in a large sample with repetition of the courses for longer duration.

1. Cerebral Palsy. NIH: National Institute of Neurological Disorders and Stroke. Available from: http://www.nlm.nih.gov/medlineplus/cerebralpalsy.html. [Last accessed on 2013 Aug 15].
2. Bax, M,Goldstein, M,Rosenbaum, P,Leviton, A,Paneth, N,Dan, B(2005).Proposed definition and classification of cerebral palsy, April 2005.Dev Med Child Neurol,47,571-576.
3. Bjornson, K,Hays, R,Graubert, C,Price, R,Won, F,Mc Laughlin, JF(2007).Botulinum toxin for spasticity in children with cerebral palsy: A comprehensive evaluation.Pediatrics,120,49-58.
4. Brittenden, J,Heys, S,Ross, J,Eremin, O(1996).Natural killer cells and cancer.Cancer,77,1226-1243.
5. Carroll, JE,Mays, RW(2011).Update on stem cell therapy for cerebral palsy.Expert Opin Biol Ther,11,463-471.
6. Delgado, MR,Hirtz, D,Aisen, M,Ashwal, S,Fehlings, DL,McLaughlin, J(2010).Practice Parameter: Pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence‑based review).Neurology,74,336-343.
7. Desloovere, K,Molenaers, G,De Cat, J,Pauwels, P,Van Campenhout, A,Ortibus, E(2007).Motor function following multilevel botulinum toxin type A treatment in children with cerebral palsy.Dev Med Child Neurol,49,56-61.
8. Diego, M.,Field, T,Hernandez‑Reif, M,Shaw, K,Friedman, L,Ironson, G(2001).HIV adolescents show improved immune function following massage therapy.Int J Neurosci,106,35-45.
9. Field, T,Morrow, C,Valdeon, C,Larson, S,Kuhn, C,Schanberg, S(1992).Massage reduces anxiety in child and adolescent psychiatric patient.J Am Acad Adolesc Psychiatry,31,125-131.
10. Hart, S,Field, T,Hernandez‑Reif, M,Lundy, B(1998).Preschoolers’ cognitive performance improves following massage therapy.Early Child Dev Care,143,59-64.
11. Hawamdeh, ZM,Ibrahim, AI,Qudah, AA(2007).Long term effect of botulinum toxin (A) in the management of calf spasticity in children with diplegic cerebral palsy.Eura Medicophys,43,311-318.
12. Hernandez‑Reif, M,Field, T,Largie, S,Diego, M,Manigat, N,Seoanes, J(2005).Cerebral palsy symptoms in children decreased following massage therapy.Early Child Dev Care,175,445-456.
13. Hurvitz, EA,Leonard, C,Ayyangar, R,Nelson, VS(2003).Complementary and alternative medicine use in families of children with cerebral palsy.Dev Med Child Neurol,45,364-370.
14. Ironson, G,Field, T,Scafidi, F,Hashimoto, M,Kumar, M,Kumar, A(1996).Massage therapy is associated with enhancement of the immune system’s cytotoxic capacity.Int J Neurosci,84,205-217.
15. Johnson, A(2005).Prevalence and characteristics of children with Cerebral Palsy in Europe.Dev Med Child Neurol,44,633-640.
16. Ketelaar, M,Vermeer, A,Hart, H,Beek, EP,Helders, PJ(2001).Effects of a functional therapy program on motorabilities of children with cerebral palsy.Phys Ther,81,1534-1545.
17. Matthews, JD,Balaban, B(2009).Management of spasticity in children with cerebral palsy.Acta Orthop Traumatol Turc,43,81-86.
18. Milky, Narkeesh A.(2012).The effect of progressive movement pattern in rehabilitation of cerebral palsy.Indian Streams Res,2,1-4.
19. Molenaers, G,Desloovere, K,De Cat, J,Jonkers, I,De Borre, L,Pauwels, P(2001).Single event multilevel botulinum toxin A treatment and surgery: Similarities and differences.Eur J Neurol,8(Suppl 5),88-97.
20. Reddihough, DS,Collins, KJ(2003).The epidemiology and causes of cerebral palsy.Aust J Physiother,49,7-12.
21. Shailaja, U,Jain, CM(2009).Ayurvedic approach towards cerebral palsy.AYU,30,158-163.
22. Shailaja, U,Rao, PN,Arun Raj, GR(2013).Clinical study on the efficacy of SamvardhanaGhrita orally and by Matrabasti in motor disabilities of Cerebral Palsy in children.Int J Res Ayurveda Pharm,4,373-377.
23. Siebes, RC,Wijnroks, L,Vermeer, A(2002).Qualitative analysis of therapeutic motor intervention programmes for children with cerebral palsy: An update.Dev Med Child Neurol,44,593-603.
24. Sorsdahl, AB,Moe‑Nilssen, R,Kaale, HK,Rieber, J,Strand, LI(2010).Changein basic motor abilities, quality of movement and everyday activities following intensive, goal‑directed, activity‑focused physiotherapy in a group setting for children with cerebral palsy.BMC Pediatr,10,26.
25. Unlu, E,Cevikol, A,Bal, B,Gonen, E,Celik, O,Kose, G(2010).Multilevel Botulinum toxin type A as a treatment for spasticity in children with cerebral palsy: Aretrospective study.Clinics,65,613-619.
26. Wely, LV,Becher, JG,Reinders‑Messelink, HA,Lindeman, E,Verschuren, O,Verheijden, J(2010).LEARN 2 MOVE 7‑12 years: Arandomized controlled trial on the effects of a physical activity stimulation program in children with cerebral palsy.BMC Pediatr,10,77.