Antimicrobial Potential of Helicanthus elastica (Desr.) Danser - A less explored Indian mistletoe Growing on Mango Trees

10.4103/2225-4110.126183

Koppala Narayana Sunil Kumar；Ariyamuthu Saraswathy；Swaminathan Amerjothy；Basaviah Ravishankar

Ethyl gallate ； Gallic acid ； Helicanthus elastica ； Loranthaceae ； Mango mistletoe

Journal of Traditional and Complementary Medicine

4卷4期（2014 / 10 / 01）

258 - 262

英文

Helicanthus elastica (Desr.) Danser (Loranthaceae) is a less-known medicinally important mistletoe species occurring in India. It is used to check abortion, and also in vesical calculi and kidney affections. There are no detailed studies reporting the antimicrobial potential of this plant. Based on the traditional use and the rich phenolic composition of the whole plant, the antimicrobial property of the alcohol extract was analyzed and the results are outlined in the present paper. For the analysis, zone of inhibition, and minimum inhibitory concentration were used, and the total activity was assayed by standard methodologies. The antimicrobial activity was studied against bacteria like Aeromonas hydrophila, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae, methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Vibrio fischeri, and a fungus Candida albicans. Of the eight tested bacteria, the alcoholic extract of H. elastica was found to be active against K. pneumoniae, A. hydrophila, E. coli, and V. fischeri at concentration ranging from 250 to 500 µg/ml. C. albicans showed inhibition only at a concentration of 2000 µg/ml.

1. Basri, DF,Fan, SH(2005).The potential of aqueous and acetone extracts of galls of Quercus infectoria as antibacterial agents.Indian J Pharmacol,37,26-29.
2. Collee, JG(ed.),Fraser, AG(ed.),Marmion, BP(ed.),Simmons, A(ed.)(1996).Mackie and Mc Cartney Practical Medical Microbiology.New York:Churchill Livingstone.
3. Cowan, MM(1999).Plant products as antimicrobial agents.Clin Microbiol Rev,12,564-582.
4. Cueva, C,Mingo, S,Muñoz‑González, I,Bustos, I,Requena, T,del Campo, R(2012).Antibacterial activity of wine phenolic compounds and oenological extracts against potential respiratory pathogens.Lett Appl Microbiol,54,557-563.
5. Cunningham, MW(2000).Pathogenesis of groupA streptococcal infections.Clin Microbiol Rev,13,470-511.
6. Eloff, JN(2004).Quantifying the bioactivity of plant extracts during screening and bioassay guided fractionation.Phytomedicine,11,370-371.
7. Friedman, M(2006).Antibiotic activities of plant compounds against non‑resistant and antibiotic resistant food borne human pathogens.Advance in microbial food safety,Washington DC, USA:
8. Hoi H, Thong HD, Tony TH, Derek L. Vibrio infections. Emedicine Specialties 2007 January. Available from: http://www.emedicine.com/med/topic2375.htm. [Last accessed on 2011 Dec 8].
9. Kirtikar KR, Basu BD. Indian Medicinal Plants. Vol. 3. Dehradoon: M/S. Bishen Singh Mahendra Singh Pal; 1935. p. 2178‑85.
10. Kuijt, J(1969).The Biology of Parasitic Flowering Plants.Berkeley:University of California Press.
11. Mary, KT,Girija, K,Ramadasan, K(1994).Partial purification of tumour reducing principle from Helicanthus elasticus (Fam. Loranthaceae).Cancer Lett,81,53-57.
12. Reynolds, JE(1996).Martindale – the Extra Pharmacopoeia.London:Royal Pharmaceutical Society of Great Britain.
13. Sunil Kumar, KN(2011).Chennai, India,The University of Madras.
14. Walsh, TR,Weeks, J,Livermore, DM,Toleman, MA(2011).Dissemination of NDM‑1 positive bacteria in the New Delhi environment and its implications for human health: An environmental point prevalence study.Lancet Infect Dis,11,355-362.