题名

The effect of Valerian root extract on the severity of pre menstrual syndrome symptoms

DOI

10.1016/j.jtcme.2015.09.001

作者

Zahra Behboodi Moghadam;Elham Rezaei;Roghaieh Shirood Gholami;Masomeh Kheirkhah;Hamid Haghani

关键词

Premenstrual syndrome ; Valerian root extract ; Mood symptoms ; Behavioral symptoms ; Physical symptoms

期刊名称

Journal of Traditional and Complementary Medicine

卷期/出版年月

6卷3期(2016 / 07 / 01)

页次

309 - 315

内容语文

英文

中文摘要

Premenstrual syndrome (PMS) is a common disorder. Due to the knowledge lack of the precise etiology of this syndrome, different treatment methods are recommended, one of them is the use of medicinal herbs. This study aimed to investigate the effect of Valerian (纈草xié cǎo) root extract on the intensity of PMS symptoms. In this double-blind clinical trial, 100 female students of Islamic Azad University, Tonekabon Branch, Mazandaran Province, Iran, with PMS were randomly divided into groups receiving Valerian (scientific name: Valeriana officinalis) and placebo in 2013. The participants received 2 pills daily in the last seven days of their menstrual cycle for 3 cycles and recorded their symptoms. The data collection tools included demographic information questionnaire, daily symptom severity questionnaire, and a provisional diagnosis of premenstrual syndrome questionnaire. Data were compared previous, one, two, and three cycles after student's intervention using and analyzed by independent t-test, paired t-test, chi-squared test, and repeated measures ANOVA in SPSS 16. A significant difference was seen in mean emotional, behavioral and physical premenstrual symptom severity in the intervention group before and after the intervention (P < 0.001). However, this difference was not statistically significant in the control group. The results of this study showed that Valerian root extract may reduce emotional, physical, and behavioral symptoms of premenstrual syndrome.

主题分类 醫藥衛生 > 中醫藥學
参考文献
  1. Adrianne, B(2000).The potential for dietary supplements to reduce Premenstrual Syndrome (PMS) symptoms.J Am Coll Nutr,19(1),3-12.
  2. Bakr, I,Ez-Elarab, HS(2010).Prevalence of premenstrual syndrome and the effect of its severity on the quality of life among medical students.Egypt J Community Med,28(2),19-30.
  3. Brahmbhatt, S,Sattigeri, BM,Shah, H,Kumar, A,Parikh, D(2013).A prospective survey study on premenstrual syndrome in young and middle aged women with an emphasis on its management.Int J Res Med Sci.,1(2),69-72.
  4. Doulatian, M,Mirabi, P,Mojab, F,Alavi, Majd, H(2009).The effect of Valerian plant on the intensity of primary dysmenorrhea.J Reprod Infertil,10(4),253-259.
  5. Ford, O,Lethaby, A,Roberts, H,Mol, BWJ(2009).Progesterone for premenstrual syndrome.Cochrane Database Syst Rev.,2,CD003415.
  6. Freeman, EW,Sammel, MD,Lin, H,Rickels, K,Sondheimer, SJ(2011).Clinical subtypes of premenstrual syndrome and responses to sertraline treatment.Obstet Gynecol,118(6),1293-1300.
  7. He, Z,Chen, R,Zhou, Y(2009).Treatment for premenstrual syndrome with Vitex agnus castus: a prospective, randomized, multi-center placebo controlled study in China.Maturitas,63(1),99-103.
  8. Jenabi, E,Asl Toghiri, M,Hejrati, P(2012).Comparison of Valerian root analgesic effects and mefenamic acid in relieving primary dysmenorrhea.Iran J Obstet Gynecol Infertil.,15(2),44-48.
  9. Khayat, S,Kheirkhah, M,BehboodiMoghadam, Z,Fanaei, H,Kasaeian, A,Javadimehr, M(2014).Effect of treatment with ginger on the severity of premenstrual syndrome symptoms.ISRN Obstet Gynecol,5,792708.
  10. Kiani Asiabar, A,Heidari, M,Mohamadi Tabar, SH,Phaghihzade, S(2009).Prevalence, Signs, symptoms, and causes of premenstrual syndrome in employed women.Bimon Sci Res,16(81),45-54.
  11. Kinrys, G,Coleman, E,Rothstein, E(2009).Natural remedies for anxiety disorders: potential use and clinical applications.Depress Anxiety,26(3),259-265.
  12. Matsumoto, T,Asakura, H,Hayashi, T(2013).Does lavender aromatherapy alleviate premenstrual emotional symptoms? A randomized crossover trial.Biopsychosoc Med,7(12),1-8.
  13. Miyasaka, LS,Atallah, ÁN,Soares, B(2006).Valerian for anxiety disorders.Cochrane Database Syst Rev,4,CD004515.
  14. Müller, D,Pfeil, T,Von den Driesch, V(2003).Treating depression comorbid with anxiety -results of an open, practice-oriented study with St John's wort WS® 5572 and Valerian extract in high doses.Phytomedicine,10(4),25-30.
  15. Pearlstein, T,Steiner, M(2008).Premenstrual dysphoric disorder: burden of illness and treatment update.J Psychiatry Neurosci,33(4),291-301.
  16. Penelope, MB,WHNP, MSN(2003).Understanding and treating PMS/PMDD.Nursing,33(13),14-17.
  17. Rezaei, A,Pashazade, M,Ahmadzade, CH,Jafari, B,Jalilzade Hedayati, M(2010).Sedative and anxiolytic effects of Valerian extract compared to diazepam in rats.Q Med Plants,9(36),169-176.
  18. Rocha Filho, EA,Lima, JC,Pinho Neto, JS,Montarroyos, U(2011).Essential fatty acids for premenstrual syndrome and their effect on prolactin and total cholesterol levels: a randomized, double blind, placebo-controlled study.Reprod Health,8,2.
  19. Sadler, C,Smith, H,Hammond, J(2010).Lifestyle factors, hormonal contraception, and premenstrual symptoms: the United Kingdom Southampton women's survey.J Womens Health,19(3),391-396.
  20. Taavoni, S,Ekbatani, N,Kashaniyan, M,Haghani, H(2012).Effect of Sedamin capsule on sleep disorder among menopausal women.J Gorgan Univ Med Sci,14(1),39-45.
  21. Wallenstein, GV,Blaisdell-Gross, B,Gajria, K(2008).Development and validation of the Premenstrual Symptoms Impact Survey (PMSIS): a disease-specific quality of life assessment tool.J Womens Health,17(3),439-450.
  22. Yonkers, KA,O'Brien, PS,Eriksson, E(2008).Premenstrual syndrome.Lancet,371(9619),1200-1210.