题名

Complementary and alternative medicine in Indian Parkinson's disease patients

DOI

10.1016/j.jtcme.2015.03.009

作者

Awadh Kishor Pandit;Deepti Vibha;Achal Kumar Srivastava;Garima Shukla;Vinay Goyal;Madhuri Behari

关键词

Parkinson's disease ; Complementary and alternative medicine ; CAM ; Ayurveda ; Acupuncture

期刊名称

Journal of Traditional and Complementary Medicine

卷期/出版年月

6卷4期(2016 / 10 / 01)

页次

377 - 382

内容语文

英文

中文摘要

Use of complementary and alternative medicine (CAM; 補充與替代醫學bǔ chōng yǔ tì dái yī xué) in Parkinson disease (PD) ranged 40-70%. The objective of this study was to determine the frequency, types and factors associated with the use of CAM in Indian PD patients. PD patients, fulfilling UKPD-Society brain-bank diagnostic-criteria, attending Movement-disorders clinic of a tertiary-care teaching hospital in India from 1st May to 15th December 2012 were enrolled. Information on socio-demographic, clinical data and treatment along with factors (source of information, benefits, harms, reason for use and cost) associated with CAM use were recorded. Out of 233 consecutive PD patients, 106 (46%) used CAM. Mean ± SD age of CAM users was 56 ± 11.2 years. Among CAM users, 72% were males, with mean age-onset 49 ± 11.16 years (P = 0.042) and 73% receiving levodopa therapy (p = 0.006). Longer duration PD, higher education (graduates and above), urban residence, and fairly good perceived health were other factors seen among CAM users. Reasons for using CAM were 'feel good factor' (73%), 9% took CAM due to side effects from allopathic-medicines. Commonly used CAM were Ayurvedic, homeopathic medicines, and acupuncture (針灸zhēn jiǔ) [74/106 (70%)]. Median CAM cost in Indian Rupees (INR) was 1000/month (USD16, range: 0-400USD/month in year 2012). Almost half of PD patients use CAM. Three-quarters of Indian CAM using PD patients believe that CAM is harmless, using it at a substantial cost. CAM-users are educated, young, urban dwellers, longer duration PD and receiving levodopa. Commonly used CAM was Ayurvedic, Homeopathic medicines and acupuncture.

主题分类 醫藥衛生 > 中醫藥學
参考文献
  1. http://www.oxforddictionaries.com/definition/english/feel-good-factor?q=feel-goodþfactor
  2. http://indiabudget.nic.in/es2011-12/estat1.pdf
  3. http://www.mdvu.org/library/ratingscales/pd/updrs.pdf
  4. Ahmad, S,Khan, MB,Hoda, MN(2012).Neuroprotective effect of sesame seed oil in 6-hydroxydopamine induced neurotoxicity in mice model: cellular, biochemical and neurochemical evidence.Neurochem Res,37,516-526.
  5. Al-Windi, A(2004).Determinants of complementary alternative medicine (CAM) use.Complement Ther Med,12,99-111.
  6. Bush, TM,Rayburn, KS,Holloway, SW(2007).Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey.Altern Ther Health Med,13,30-35.
  7. Calabrese, C,Gregory, WL,Leo, M,Kraemer, D,Bone, K,Oken, B(2008).Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, Placebo-controlled trial.J Altern Complement Med,14,707-713.
  8. Conboy, L,Edshteyn, I,Garivaltis, H(2009).Ayurveda and Panchakarma: measuring the effects of a holistic health intervention.ScientificWorldJournal,9,272-280.
  9. Eisenberg, DM,Davis, RB,Ettner, SL(1998).Trends in alternative medicine use in the United States, 1990e1997: results of a follow-up national survey.JAMA J Am Med Assoc.,280,1569-1575.
  10. Ferry, P,Johnson, M,Wallis, P(2002).Use of complementary therapies and non-prescribed medication in patients with Parkinson's disease.Postgrad Med J.,78,612-614.
  11. Goetz, CG,Poewe, W,Rascol, O(2004).Movement Disorder Society Task Force report on the Hoehn and Yahr staging scale: status and recommendations.Mov Disord Off J Mov Disord Soc,19,1020-1028.
  12. Hanssen, B,Grimsgaard, S,Launsø, L,Fønnebø, V,Falkenberg, T,Rasmussen, NK(2005).Use of complementary and alternative medicine in the Scandinavian countries.Scand J Prim Health Care,23,57-62.
  13. Henneberg, A(1998).Additional therapies in Parkinson's disease patients: useful tools for the improvement of the quality of life or senseless loss of resources?.J Neurol.,245(suppl 1),S23-S27.
  14. Hughes, AJ,Daniel, SE,Kilford, L,Lees, AJ(1992).Accuracy of clinical diagnosis of idio-pathic Parkinson's disease: a clinico-pathological study of 100 cases.J Neurol Neurosurg Psychiatry,55,181-184.
  15. Katzenschlager, R,Evans, A,Manson, A(2004).Mucuna pruriens in Parkinson's disease: a double blind clinical and pharmacological study.J Neurol Neurosurg Psychiatry,75,1672-1677.
  16. Kim, SR,Lee, TY,Kim, MS,Lee, MC,Chung, SJ(2009).Use of complementary and alternative medicine by Korean patients with Parkinson's disease.Clin Neurol Neurosurg,111,156-160.
  17. Lökk, J,Nilsson, M(2010).Frequency, type and factors associated with the use of complementary and alternative medicine in patients with Parkinson's disease at a neurological outpatient clinic.Park Relat Disord,16,540-544.
  18. Lynöe, N.(1992).Ethical and professional aspects of the practice of alternative medicine.Scand J Soc Med,20,217-225.
  19. Manyam, BV,Sánchez-Ramos, JR(1999).Traditional and complementary therapies in Parkinson's disease.Adv Neurol,80,565-574.
  20. Nilsson, M,Trehn, G,Asplund, K(2001).Use of complementary and alternative medicine remedies in Sweden. A population-based longitudinal study within the northern Sweden MONICA Project. Multinational Monitoring of trends and determinants of cardiovascular disease.J Intern Med.,250,225-233.
  21. Pearson, NJ,Chesney, MA(2007).The CAM Education Program of the National Center for Complementary and Alternative Medicine: an overview.Acad Med J Assoc Am Med Coll,82,921-926.
  22. Rabey, JM,Vered, Y,Shabtai, H,Graff, E,Korczyn, AD(1992).Improvement of parkinsonian features correlate with high plasma levodopa values after broad bean (Vicia faba) consumption.J Neurol Neurosurg Psychiatry,55,725-727.
  23. Rajendran, PR,Thompson, RE,Reich, SG(2001).The use of alternative therapies by patients with Parkinson's disease.Neurology,57,790-794.
  24. Ryan, M,Johnson, MS(2002).Use of alternative medications in patients with neuro-logic disorders.Ann Pharmacother,36,1540-1545.
  25. Singh, HK,Dhawan, BN(1997).Neuropsychopharmacological effects of the ayurvedic nootropic Bacopa monneri Linn. (Bramhi).Indian J Pharmacol,29,359-365.
  26. Tan, LCS,Lau, P-N,Jamora, RDG,Chan, ESY(2006).Use of complementary therapies in patients with Parkinson's disease in Singapore.Mov Disord Off J Mov Disord Soc.,21,86-89.
  27. Tomlinson, CL,Stowe, R,Patel, S,Rick, C,Gray, R,Clarke, CE(2010).Systematic review of levodopa dose equivalency reporting in Parkinson's disease.Mov Disord Off J Mov Disord Soc.,25,2649-2653.