题名

Neuroprotective potency of some spice herbs, a literature review

DOI

10.1016/j.jtcme.2018.01.002

作者

Mohammad Reza Khazdair；Akbar Anaeigoudari；Milad Hashemzehi；Reza Mohebbati

关键词

Traditional medicine ； Medicinal plant ； Spice ； Memory ； Nervous system

期刊名称

Journal of Traditional and Complementary Medicine

卷期/出版年月

9卷2期（2019 / 04 / 01）

页次

98 - 105

内容语文

英文
中文摘要

In recent years, growing attention has been given to traditional medicine. In traditional medicine a large number of plants have been used to cure neurodegenerative diseases such as Alzheimer's disease (AD) and other memory related disorders. Crocus sativus (C. sativus), Nigella sativa (N. sativa), Coriandrum sativum (C. sativum), Ferula assafoetida (F. assafoetida), Thymus vulgaris (T. vulgaris), Zataria multiflora (Z. multiflora) and Curcuma longa (C. longa) were used traditionally for dietary, food additive, spice and various medicinal purposes. The Major components of these herbs are carotenoids, monoterpenes and poly phenol compounds which enhanced the neural functions. These medicinal plants increased anti-oxidant, decreased oxidant levels and inhibited acetylcholine-esterase activity in the neural system. Furthermore, neuroprotective of plants occur via reduced pro-inflammatory cytokines such as IL-6, IL-1β, TNF-α and total nitrite generation. Therefore, the effects of the above mentioned medicinal and their active constituents improved neurodegenerative diseases which indicate their therapeutic potential in disorders associated with neuro-inflammation and neurotransmitter deficiency such as AD and depression.
主题分类 醫藥衛生 > 中醫藥學
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