製備微膠囊抗菌口罩

Preparation of the antimicrobial masks with herbal microcapsules

10.6840/cycu201600475

林耕樂

中藥 ； 微膠囊 ； 抗菌 ； 電漿改質 ； 口罩 ； herb medicine ； microcapsules ； antibacterial rate ； plasma ； mask

中原大學生物環境工程研究所學位論文

2016年

碩士

王雅玢;游勝傑

繁體中文

工業發展的開始是科技革新的第一頁，但也展開了空氣汙染快速增加的序幕，肺部疾病及許多慢性下呼吸道疾病隨著工業科技的發展也躍升成國人十大死因之一。空氣中含有包含懸浮微粒及細懸浮微粒等各種對人體有害的物質，其中生物氣膠是導致過敏的因素之一。生物氣膠量不但會隨著人口數量增加也受各地溫度、相對溼度等因素所影響，尤其現今人口密集，其帶來的影響不容忽視，為避免生物氣膠直接藉由空氣攝入或飛沫傳染，本研究將製備抗菌口罩的製作會針對生物氣膠抗菌測試。 一般抗菌劑部分選用化學藥品，由於中藥對人體較為友善，其中含有的類黃酮成分亦有抗菌效果，因此選定中藥為抗菌劑，本研究選用黃芩以及防風兩種中藥，黃芩萃液0.2mg/L對於大腸桿菌與金黃色葡萄球菌之抗菌率皆能達到99.999 %以上，由最小抑菌濃度觀察出其對金黃色葡萄球菌抗菌效率較快且佳；中藥防風萃液0.5mg/L對於大腸桿菌與金黃色葡萄球菌之抗菌率也皆能達到99.999% %以上；由最小抑菌濃度實驗可以觀察出其對大腸桿菌抗菌效率較佳，因此利用兩種依不同比例混和後進行抗菌測試，結果顯示最佳比例為對大腸桿菌為7(黃芩)：3(防風)，抗菌效果能達到99.997%以上，對金黃色葡萄球菌為2(黃芩)：8(防風)抗菌效果亦能達到94%以上。 研究亦針對中藥黏附性方面進行測試，將中藥製成微膠囊以增加中藥黏附性及抗菌性，比較三種不同微膠囊製作流程，分別為微膠囊(未經交聯反應)、加入乳化交聯反應之微膠囊、以及交聯反應的微膠囊，進行抗菌測試。針對大感菌測試結果，結果顯示經交聯反應之微膠囊效果最佳，對大腸桿菌及金黃色葡萄球菌皆可以達到可以以達到99.997%以上抗菌率。微膠囊黏附強度利用AATCC100做為測試，經過清洗100次後，為交聯反應為膠囊黏附效果最佳。 本研究取交聯反應微膠囊作為最終實驗用途，並搭配布料電漿改質(50w改質時間1分鐘)，測試三種不同布料，結果為不織布呈現效果最佳，其微膠囊殘留量最多，實場測試效果亦最優秀。

With the rapid development of science and technology , air pollution is increasingly attention by people. Respiratory and chronic lower respiratory diseases has become one of the national top ten causes of death in recent years. In order to protect the respiratory this research will preparation of masks for air biological aerosol by using herb medicine. In the research of the mixture of herb medicine , the best proporation of saposhinikovia and scutellaria toInhibition of E.coli is 7:3, to S.aureus is 2:8. And in research we make herb microcapsules to increase the adhesion and to extend antibacterial. Through microcapsules the antibacterial time can be extended to 24 hours ,and the antibacterial rate to E.coli and S.aureus can still maintain in 99.997%. After increase the adhesion of herb medicine, in research we also modified the filter fabric by use plasma. The washability test shows that plasma modified increase the hydrophilic of fabric.After 100 times wash the residual rate of three different fabric(cotton, polyester, nonwoven) is better than nonmodified sample.

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