题名

過敏性鼻炎評分量表(SFAR)與臨床病程之相關性研究

并列篇名

Correlation Study of the Score for Allergic Rhinitis and Clinical Course in Adolescence of Yilan County

DOI

10.6516/TJTCM.201303_16(1).0010

作者

游美鳳(Mei-Feng Yu);呂萬安(Wan-An Lu)

关键词

過敏性鼻炎評分量表 ; 間歇性 ; 持續性 ; 青少年 ; the score for allergic rhinitis ; intermittent ; persistent ; adolescence

期刊名称

中醫藥研究論叢

卷期/出版年月

16卷1期(2013 / 03 / 30)

页次

149 - 168

内容语文

繁體中文

中文摘要

目的:過敏性鼻炎是所有過敏疾病中最常見,估計全球患有超過 5億的過敏性鼻炎患者,而台灣地區的盛行率愈來愈高,本病與氣喘為同一發病過程,在氣道不同部位的表現,過敏性鼻炎的診斷,至今沒有國際公認的標準,通常會結合患者的病史、典型的症狀及一或二項的實驗室檢查,做為研究或臨床工作中的診斷標準,過敏性鼻炎評分量表(The Score For Allergic Rhinitis 簡稱SFAR)已經被證明是一種有效的篩選診斷工具,因此本研究乃針對青少年進行 SFAR評量,進一步調查是否與過敏性鼻炎各項相關危險因子有所關聯,希望能夠幫助並提供中西醫師在臨床上之參考。方法:本研究採取橫斷式問卷調查法,以方便取樣為原則,第一階段選取宜蘭縣某高職學生830位進行SFAR問卷調查,第二階段從SFAR得分大於等於7分者之中,隨機選出125 位符合取樣標準之個案,進行問卷調查。結果:830位受訪者中過敏性鼻炎發生率為49.8%,其中男性有143人(34.6%),佔男性人數的42.4%,女性有270人(65.4%),佔女性人數的54.8%;收案125名過敏性鼻炎患者,其SAFR得分平均為 10.7分,最低分為7分,最高分為15分,其中得13分人數最多,有26位(20.8%),得7分人數最少,只有2位(1.6%);中輕度間歇性者15位(12.0%),中重度間歇性者58位(46.4%),輕度持續性者3位(2.4%),中重度持續性者49位(39.2%);過敏性鼻炎患者之病程和SFAR呈現正相關(r=0.351,p<0.01),此外腰圍與身體質量指數也具有正相關(r=0.843,p<0.01)。結論:隨著病程的加長,過敏性鼻炎的嚴重程度也會增加,換言之過敏性鼻炎如果沒有得到良好的控制,就會增加氣喘發生的可能性。SFAE不同分數所代表的不同生理意義值得未來進一步去研究,並可作為臨床中醫學的輔助與參考。

英文摘要

The allergic rhinitis was the most common disease in all allergic diseases. There were more than five hundred million patients suffers from allergic rhinitis in the world and more and more prevalence in Taiwan. There were all the same course between allergic rhinitis and athma, but the different airway appearance. There was no international standard diagnosis of allergic rhinitis so far. In general, the diagnosis standard of clinics and study was according to combining medical history, typical symptom and one or two kind of laboratory examination results. The score for allergic rhinitis (SFAR) was already approved as an effective screening and diagnosis tool in medicine. The purpose of the study was to assessment SFAR of adolescence and further correlation study between SFAR and related risk factors. We hope the study could make the favor of clinical works in traditional medicine and modern medicine. Methods: This study used the cross-sectional questionnaire survey with the convenience sampling method. The study subjects of the first step were 830 students with questionnaire survey of the SFAR. The study subjects of the second step were 125 students that came from equal or greater than 7 score of the SFAR with random. Results: We found that allergic rhinitis prevalence was 49.8% of 830 subjects that contained 143 males (34.6%) that the number of females accounted for 42.4% and 270 females (65.4%) that the number of females accounted for 65.4%. The average score of SFAR was 10.7 all the 125 study subjects and lowest score of SFAR was 7, the highest score of SFAR was 15, beside 26 subjects (20.8%) were score 13 with highest subjects in the study subjects and 2 subjects (1.6%) were score 7 with lowest subjects in the study subjects. 15 subjects (12.0%) were moderate to mild intermittent and 58 subjects (46.4%) were moderate to severe intermittent and 3 subjects were mild persistent, 49 subjects were moderate to severe persistent. There was significant positive correlation (r = 0.351, p<0.01) between clinical course and SFAR, beside all the same between waist circumference and body mass index (r= 0.843, p<0.01). Conclusion: The more severity of allergic rhinitis was appeared following more clinical course. In other words, there was no good control of allergic rhinitis could increase the propobility of athma. It was valued to further study that the different score of SFAR represent different physiology and it was beneficial to the clinical traditional Chinese medicine.

主题分类 醫藥衛生 > 中醫藥學
醫藥衛生 > 藥理醫學
参考文献
  1. Annesi-Maesano, I,Didier, A,Klossek, M,Chanal, I,Moreau, D,Bousquet, J(2002).The score for allergic rhinitis (SFAR): a simple and valid assessment method in population studies.Allergy,57,107-14.
  2. Berger, WE(2004).Allergic rhinitis in children : diagnosis and management strategies.Paediatr Drugs,6,33-50.
  3. Bousquet, J,Gaugris, S,Kocevar, VS,Zhang, Q,Yin, DD,Polos, PG,Bjermer, L(2005).Increased risk of asthma attacks and emergency visits among asthma patients with allergic rhinitis: a subgroup analysis of the investigation of montelukast as a partner agent for complementary therapy.Clin Exp Allergy,35,723-7.
  4. Bousquet, PJ,Bousquet-Rouanet, L,Co Minh, HB,Urbinelli, R,Allaert, FA,Demoly, P(2007).ARIA (Allergic Rhinitis and Its Impact on Asthma) classification of allergic rhinitis severity in clinical practice in France.Int Arch Allergy Immunol.,143,163-9.
  5. Cauwenberge, PV,Belder, TD,Vermeiren, J,Kaplan, A(2003).Global Resources in Allergy (GLORIA): allergic rhinitis and allergic conjunctivitis.Clinical & Experimental Allergy Reviews,3,46-50.
  6. Dalal, AA,Stanford, R,Henry, H,Borah, B(2008).Economic burden of rhinitis in managed care: a retrospective claims data analysis.Ann Allergy Asthma Immunol.,101,23-9.
  7. Kellberger, J,Dressel, H,Vogelberg, C,Leupold, W,Windstetter, D,Weinmayr, G,Genuneit, J,Heumann, C,Nowak, D,von Mutius, E,Radon, K(2012).Prediction of the incidence and persistence of allergic rhinitis in adolescence: a prospective cohort study.J Allergy Clin Immunol.,129,397-402.
  8. Members of the Workshops(2004).ARIA in the pharmacy: management of allergic rhinitis symptoms in the pharmacy. Allergic rhinitis and its impact on asthma.Allergy,59,373-87.
  9. Rhodes, HL,Sporik, R,Thomas, P,Holgate, ST,Cogswell, JJ(2001).Early life risk factors for adult asthma: a birth cohort study of subjects at risk.J Allergy Clin Immunol.,108,720-5.
  10. Ryan, D,Levy, M,Morris, A,Sheikh, A,Walker, S(2005).Management of allergic problems in primary care: time for a rethink?.Prim Care Respir J.,14,195-203.
  11. Scadding, GK,Keith, PK(2008).Fluticasone furoate nasal spray consistently and significantly improves both the nasal and ocular symptoms of seasonal allergic rhinitis: a review of the clinical data.Expert Opin Pharmacother,9,2707-15.
  12. Stewart, MG(2008).Identification and management of undiagnosed and undertreated allergic rhinitis in adults and children.Clin Exp Allergy,38,751-60.
  13. 王九華、馬素華、楊賢鴻、陳盈霖、陳偉君(2008)。以台灣簡明版世界衛生組織生活品質問卷為基礎的過敏性鼻炎問卷之發展。護理雜誌,55,49-60。
  14. 王光輝、王袁園、周明輝(2009)。變應性鼻炎評分在變應性鼻炎診斷中的應用。臨床醫學,29,22-24。
  15. 吳維峰、林應然、吳振龍(2004)。氣喘與過敏性鼻炎之關聯及治療。北巿醫學雜誌,1,261-267。
  16. 周琳霓(2008)。消除環境中的過敏因子。健康世界,2008(12月),19-22。
  17. 林秀珍、李仲民、謝嘉成(2006)。過敏性鼻炎與氣喘之相互關係探討。繼續教育,22,144-152。
  18. 林清榮、王怡芬(2001)。鼻炎的流行病學。中華民國耳鼻喉科醫學雜誌,36,7-10。
  19. 徐茂銘(2004)。過敏性鼻炎的治療原則及趨勢。臺北巿醫師公會會刊,48,52-59。
  20. 張羅、顧之燕、鄭銘、韓德民(2009)。過敏性鼻炎患病狀況研究。中國耳鼻咽喉頭頸外科,16,665-668。
  21. 許昱、陶澤璋(2008)。變態反應疾病的自然進程及干預。中華臨床免疫和變態反應雜誌,2,122-126。
  22. 鄭國揚、林昭庚、蔡銘修、周昌德(2000)。過敏性鼻炎之細胞免疫學研究。耳鼻喉科醫學雜誌,35,16-23。
  23. 謝昌成、陳建甫、劉鎮嘉(2006)。過敏性鼻炎。基層醫學,20,346-51。