题名

異位性皮膚炎(Atopic Dermatitis)中醫文獻回顧

并列篇名

Review of Chinese Medicine Archives and Modern Studies about Atopic Dermatitis

DOI

10.6516/TJTCM.201803_21(1).0003

作者

黃奎曄(Kuei-Yeh Huang);林立偉(Li-wei Lin);蔡金川(Chin-Chuan Tsai);吳龍源(Lung-Yuan Wu)

关键词

異位性皮膚炎 ; 中醫藥 ; 文獻回顧 ; Atopic dermatitis (AD) ; Chinese medicine ; article review

期刊名称

中醫藥研究論叢

卷期/出版年月

21卷1期(2018 / 03 / 30)

页次

29 - 41

内容语文

繁體中文

中文摘要

異位性皮膚炎是一種慢性、反覆發作的皮膚疾病,時常從年輕時就開始侵犯身體,對於患者的生活品質、人際關係、家庭照護,都造成一定的負擔,而目前的治療方式仍以西醫為主軸。雖然西醫治療效果不錯,但也有許多患者擔心西藥所造成的副作用,因此轉而求助於中醫治療,並希望藉由根本將異位性皮膚炎完全治癒,不再發作為治療目標。本回顧查找了古代典籍中描述接近於異位性皮膚炎的相關文獻,了解中醫是如何描述此種疾病,並試著將文獻敘述與臨床所見症狀結合在一起,讓古今醫學的連結更加緊密。另外,也翻閱了近十年的相關研究報導,發現異位性皮膚炎患者的證型以「脾虛濕熱」為最大宗,「血虛風燥」及「濕熱內蘊」則分別占了第二及第三。在相關臟腑方面,以「脾」對整個疾病的影響最大,而外邪中則以「火、熱」與「濕」分別名列一、二。在整個文獻的回顧過程中,我們希望從中尋找合適的治療方向,希望不只能為臨床治療提供參考,也能對未來的研究能有所貢獻。

英文摘要

Atopic dermatitis (AD) is a chronic and relapsing disease which often strike a person from young ages and cause negative effects on life qualities, social networks and health care system. In our society, Western medicine is still the major therapy for AD patients to choose and the consequences are fine under most situations. However, considering the side effects of taking Western medicine for a period of time, some patients turn their eyes toward Chinese medicine for not only to alleviate those annoying symptoms but to cure AD through whole system adjustment. In this review, we tried to realize the thinking process of Chinese medicine science through searching some of the archives and to establish a closer connection between traditional illustrations and modern symptoms. In the same time, we assembled some of modern studies in 10 years found out that the most seen pattern/syndrome is "spleen deficiency with dampness encumbrance", which "blood deficiency and wind-dryness" at the second place and "spreading dampness-heat" takes the third. As the Viscera and Bowels part, "Spleen" plays the major role. Talking about External Pathogen, "Heat/Fire" affects most while "Dampness" is the second. We hope to summarize a suitable therapy direction during this review process which not only to offer a reference for clinical work but to promote our future researches.

主题分类 醫藥衛生 > 中醫藥學
醫藥衛生 > 藥理醫學
参考文献
  1. 林敬凡、劉碧華、黃子玶、連心瑜、陳俊良、顏宏融(2013)。異位性皮膚炎患者使用中醫藥型態分析研究。中醫藥雜誌,24(2),293-300。
    連結:
  2. (1993).Consensus Report of the European Task Force on Atopic Dermatitis. Severity Scoring of Atopic Dermatitis: The SCORAD Index.Dermatology,186,23-31.
  3. Pathogenesis, clinical, manifestations and diagnosis of atopic dermatitis (eczema), UpToDate® 2016
  4. 宋陳無擇(2007)。三因極一病證方論。中國中醫藥出版社。
  5. 唐孫思邈(1975)。急備千金要方。台北:地球出版社有限公司。
  6. 清吳謙(1977)。醫宗金鑑。台北:大中國圖書公司。
  7. 清許克昌、曲祖貽點校(1987)。外科證治全書。人民衛生出版社。
  8. 隋巢元方、陳九如校訂(1975)。巢氏諸病源候總論。宇宙醫藥出版社。
  9. Asher, MI,Montefort, S,Bjorksten, B,Lai, CK,Strachan, DP,Weiland, SK(2006).Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry crosssectional surveys.Lancet,368,733-43.
  10. Brenninkmeijer, E.E.A.,Schram, M.E.,Leeflang, M.M.G.,Bos, J.D.,Spuls, Ph.I.(2008).Diagnostic criteria for atopic dermatitis: a systematic review.British Journal of Dermatology,158,754-65.
  11. Chen, Hsing-Yu,Lin, Yi-Hsuan,Wu, Jau-Ching,Hu, Sindy,Yang, Sien-hung,Chen, Jiun-Liang,Chen, Yu-Chun,Lo, Su-Shun(2015).Use of traditional Chinese medicine reduces exposure to corticosteroid among atopic dermatitis children: A 1-year follow-up cohort study.Journal of Ethnopharmacology,259,189-96.
  12. Chu, Chia-Yu,Lee, Chi-Hung,Shih, I-Hsin,Chen, Hsiu-Chin,Huang, Po-Han,Yang, Wen-Jen,Wang, Wen-Jen,Chen, Yi-Ju,Sheu, Hamm-Ming,Wang, Wei-Ming,Lee, Woan-Ruoh,Lo, Yuan-Hsin,Dai, Yang-Shia,Wang, Li-Fang,Tsai, Tsen-Fang,Yang, Chih-Hsun(2015).Taiwanese Dermatological Association consensus for the management of atopic dermatitis.Dermatologica Sinica,33,220-30.
  13. Eichenfield, Lawrence F.,Tom, Wynnis L.,Chamlin, Sarah L.,Feldman, Steven R.,Hanifin, Jon M.,Simpson, Eric L.,Berger, Timothy G.,Bergman, James N.,Cohen, David E.,Cooper, Kevin D.,Cordoro, Kelly M.,Davis, Dawn M.,Krol, Alfons,Margolis, David J.,Paller, Amy S.,Schwarzenberger, Kathryn,Silverman, Robert A.,Williams, Hywel C.,Elmets, Craig A.,Block, Julie,Harrod, Christopher G.,Begolka, Wendy Smith,Sidburyr, Robert(2013).Guidelines of care for the management of atopic dermatitis.J AM ACAD DERMATOL,70(2),338-51.
  14. Hon, K.L.E.,Leung, T.F.,Ng, P.C.,Lam, M.C.A.,Kam, W.Y.C.,Wong, K.Y.,Lee, K.C.K.,Sung, Y.T.,Cheng, K.F.,Fok, T.F.,Fung, K.P.,Leung, P.C.(2007).Efficacy and tolerability of a Chinese herbal medicine concoction for treatment of atopic dermatitis: a randomized, double-blind, placebo-controlled study.British Journal of Dermatology,157,357-63.
  15. Hwang, CY,Chen, YJ,Lin, MW,Chen, TJ,Chu, SY,Chen, CC,Liu, HN(2010).Prevalence of atopic dermatitis, allergic rhinitis and asthma in Taiwan: a national study 2000 to 2007.Acta Derm Venereol,90(6),589-94.
  16. Kobayashi, Hiromi,Ishii, Masamitsu,Takeuchi, Satoshi,Tanaka, Yoichi,Shintani, Takahiro,Yamatodani, Atsushi,Kusunoki, Tadashi,Furue, Masutaka(2010).Efficacy and Safety of a Traditional Herbal Medicine, Hochu-ekki-to in the Longterm Management of Kikyo (Delicate Constitution) Patients with Atopic Dermatitis: A 6-month, Multicenter, Double-blind, Randomized, Placebocontrolled Study.eCAM,7(3),367-73.
  17. Leshem, Y.A.,Hajar, T.,Hanifin, J.M.,Simpson, E.L.(2015).What the Eczema Area and Severity Index score tells us about the severity of atopic dermatitis: and interpretability study.British Journal of Dermatology,172,1353-57.
  18. Schmitt, J,Langan, S,Deckert, S,Svensson, A,Kobyletzki, L,Thomas, K,Spuls, P(2013).Assessment of clinical signs of atopic dermatitis: A systematic review and recommendation.J Allergy Clin Immunol,132,1337-47.
  19. Spergel, JM(2010).From atopic dermatitis to asthma: the atopic march.Ann Allergy Asthma Immunol,105,99-106.
  20. 中華中醫藥學會皮膚科專業委員會(2013)。特應性皮炎中醫診療方案專家共識。中國中西醫結合皮膚性病學雜誌,12(1),60-61。
  21. 毛娟娟、朱明芳、張曉玲(2014)。石榴皮軟膏治療特應性皮炎30 例臨床觀察。湖南中醫雜誌,30(4),23-29。
  22. 何丹、林青、王妍(2009)。特應性皮炎的中醫辨證及用藥規律。雲南中醫學院學報,32(4),66-70。
  23. 吳柳、隆紅艷(2016)。兒童特應性皮炎中醫外治進展。遼寧中醫藥大學學報,18(3),82-84。
  24. 吳曉涵、張壁月(2015)。淺談纖聚蛋白(filaggrin)與異位性皮膚炎。J Bilmed Lab Sci,27(2),35-40。
  25. 李玉華、李勝君、曹曉煥、許繼宗、楊建宇、李揚(2011)。特應性皮炎的研究進展。中國中醫藥現代遠程教育,9(23),169-174。
  26. 林穎、黃楚君、朱海莉、莫秀梅(2011)。陳達燦教授以中醫外治法治療特應性皮炎經驗介紹。新中醫,43(5),151-153。
  27. 柳自彬、高鵬、楊京慧(2016)。升降散治療濕疹皮炎應用體會。中國實用醫藥,11(3),183-184。
  28. 孫源梅、刁慶春(2013)。中醫藥治療特應性皮炎研究概況。四川中醫,31(8),189-190。
  29. 張冰、梁碧欣、吳元勝、李紅毅、禤國維(2014)。基於數據挖掘技術的特應性皮炎辨治規律分析。中華中醫藥學刊,32(5),1029-1032。
  30. 黃子玶、顏宏融(2010)。異位性皮膚炎的中西醫觀點與相關實證研究進展。中醫藥研究論叢,13(2),23-38。
  31. 黃偉星(2012)。潤膚中藥在皮膚病中的臨床應用。中國實用醫藥,7(6),177-178。
  32. 楊玉峰、劉少芬(2015)。生石膏在治療血虛風燥型特應性皮炎中的臨床應用。河北中醫藥學報,30(4),35-36。
  33. 楊維傑編譯(2011)。黃帝內經素問譯解。志遠書局。
  34. 溫曉文、莫秀梅、劉俊峰、歐愛華、薛素琴、陳達燦、呂愛平(2015)。基於心脾相關理論對特應性皮炎中醫證候要素的臨床研究。時珍國醫國藥,26(1),167-169。
  35. 劉熾、溫曉文、黃楚君、陳達燦(2011)。古代中醫對特應性皮炎疾病特徵的認識鈎玄。新中醫,43(4),127-128。
  36. 劉靜、傅杰、喻桃(2009)。特應性皮炎中醫證治研究進展。江西中醫藥,40(7),75-77。
  37. 蔣有讓、金夢祝、刁慶春、熊霞、史丙俊(2014)。特應性皮炎辨證分型的聚類分析研究。光明中醫,29(6),1184-1186。
  38. 遲慧彥、郎娜、黃堯洲、姚春海、余遠遙、趙一丁、李云峰、崔晗(2012)。鎮心安神法治療特應性皮炎的理論與實踐。中醫雜誌,53(9),747-760。
  39. 羅瑞靜、柴維漢(2013)。從“脾”論治兒童異位性皮膚炎的可行性探討。中華中醫藥學刊,31(8),1717-1719。
  40. 饒琪、宋瑜(2014)。中醫藥治療特應性皮炎研究進展。浙江中西醫結合雜誌,24(7),651-654。
被引用次数
  1. 林庭淇,林沛穎(2023)。中醫治療異位性皮膚炎之病例報告。台北市中醫醫學雜誌,29(2),49-59。