C型肝炎與腎臟移植

Hepatitis C and Kidney Transplantation

10.6340/KD.2016.28(1).05

陳致中(Chih-Chung Chen)；吳明儒(Ming-Ju Wu)；徐國雄(Kuo-Hsiung Shu)；游棟閔(Tung-Min Yu)；鄭志雄(Chi-Hung Cheng)

C型肝炎 ； 腎臟移植 ； 改善全球腎臟病預後組織臨床指引 ； hepatitis C ； kidney transplantation ； KDIGO guideline

腎臟與透析

28卷1期（2016 / 03 / 01）

19 - 21

繁體中文

C型肝炎在慢性腎臟病第五期的發生率，比一般大眾的比例高，所以這些病人有許多在考慮換腎時，可能之前沒有被診斷出C型肝炎或是甚至從來沒有徹底評估過肝病。在一些研究，這類病人幾乎有25%肝臟切片已經有明顯的纖維化或肝硬化。C型肝炎對移植病人和移植預後仍然是很有挑戰性的臨床議題。改善全球腎臟病預後組織的臨床指引，提供了處理腎移植病人的C型肝炎一些實用的建議。

CKD Stage 5 than in the general population. As a consequence, many of these patients present for consideration of kidney transplantation with either previously undiagnosed disease or never having had a thorough evaluation of their liver disease. In some studies, almost 25% of these patients already have significant fibrosis or cirrhosis on liver biopsy. The impact of HCV infection on the candidacy and post-transplant outcomes remains a challenging clinical issue. KDIGO guidelines have offered some practical suggestions for management of hepatitis C in kidney transplantation.