题名

乳癌化學治療引起味覺異常之病例報告

并列篇名

Chemotherapy-Induced Dysguesia Following Breast Cancer Surgery: A Case Report

DOI

10.30030/JTCGM.202006_(25).0004

作者

王育才(Wang, Yu-Tsai)；柯馨婷(Ko, Hsin-Ting)；陳正傑(Cheng, Jeng Jay)；呂琇蓉(Lu, Hsiu-Jung)；賴英秀(Lay, Ing Shiow)

关键词

乳癌 ； 中醫 ； 味覺異常 ； 化學治療 ； 賀爾蒙治療 ； breast cancer ； Chinese medicine ； dysgeusia ； chemotherapy ； hormone therapy

期刊名称

中醫婦科醫學雜誌

卷期/出版年月

25期（2020 / 06 / 01）

页次

30 - 43

内容语文

繁體中文
中文摘要

本病例為一位50歲右側乳房惡性腫瘤女性病患，因外科手術切除之後併用化學治療與賀爾蒙治療藥物之副作用而引起味覺異常（dysgeusia）。本篇病例報告這個中西醫整合治療過程中，引起味覺異常的歷程、病因病機與運用中藥方劑治療之成效。我們認為中醫中藥方劑調理與治療作為輔助及替代性療法，對於西醫治療惡性乳癌患者術後化學治療與賀爾蒙治療副作用的改善、味覺異常的治療與生活品質之提昇確實成效良好。這篇病例報告同時也指出對於這個議題未來可能的研究方向。
英文摘要

This is a case of a 50 years old female with right breast cancer, exhibiting dysgeusia after combined chemotherapy and hormonal therapy post a surgical excision. This case report described the process of taste alteration, its pathophysiology and the efficacy of using Chinese medicine treatment. We consider Chinese Medicine treatment as an effective complementary and alternative treatment to improve the side effects of chemotherapy and hormonal therapy after surgery, to treat the following dysgeusia, and to elevate life quality of the patients. This case report also indicated some possible research directions on this issue in the future.
主题分类 醫藥衛生 > 中醫藥學
参考文献
  1. 自由時報：肺癌蟬聯癌症死因之首，乳癌最折壽，2018 年 6 月 15 日，取自https://news.ltn.com.tw/news/life/breakingnews/2459565。
  2. Barlow, Linda A.(2015).Progress and renewal in gustation: new insights into taste bud development.Development,142(21),3620-3629.
  3. Doty, Richard L.(2018).Measurement of chemosensory function.World J Otorhinolaryngol Head Neck Surg,4(1),11-28.
  4. Goldman, Lee,Schafer, Andrew I.(2015).Goldman-Cecil Medicine.USA:Elsevier Saunders.
  5. Jayakaran, Trophimus, G.(2014).The effect of drugs in the oral cavity - A review.Journal of Pharmaceutical Sciences and Research,6(2),89-96.
  6. Kayl, Anne E.,Meyers, Christina A.(2006).Side-effects of chemotherapy and quality of life in ovarian and breast cancer patients.Current Opinion in Obstetrics and Gynecology,18(1),24-28.
  7. Maheswaran, T,Abikshyeet, P,Sitra, G,Gokulanathan, S,Vaithiyanadane, V,Jeelani, S.(2014).Gustatory dysfunction.J Pharm Bioallied Sci,6(Suppl 1),S30-S33.
  8. Mukherjee, N,Delay, ER(2011).Cyclophosphamide-induced disruption of umami taste functions and taste epithelium.Neuroscience,192,732-745.
  9. Murtaza, B,Hichami, A,Khan, AS,Ghiringhelli, F,Khan, NA(2017).Alteration in Taste Perception in Cancer: Causes and Strategies of Treatment.Front Physiol,8,134.
  10. Nurgali, K(ed.),Jagoe, RT(ed.),Abalo, R.(ed.)(2018).Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?.Front Pharmacol.,9,245.
  11. Yagi, T,Asakawa, A,Ueda, H,Ikeda, S,Miyawaki, S,Ini, A(2013).The role of zinc in the treatment of taste disorders.Recent Pat Food Nutr Agric.,5(1),44-51.
  12. 李培生（編）(2007).傷寒卒病論.台灣:知音出版社.
  13. 蔣健(2018)。鬱證發微─鬱證味覺，舌覺異常論。上海中醫藥雜誌，52(3)，15-20。
被引用次数
  1. 趙恆翊,呂琇蓉,王育才(2020)。乳癌的中西醫觀點暨自然療法初探。中醫內科醫學雜誌，18(2)，35-47。
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