题名

中醫藥改善乳癌病人荷爾蒙治療後關節疼痛之病例報告

并列篇名

A breast cancer case report: Using Traditional Chinese Medicine to alleviate hormone therapy-induced arthralgia

DOI

10.30030/JTCGM.202212_29(2).0007

作者

劉丁鳳(Ding Fong Liu);陳婉伶(Wan-Ling Chen)

关键词

中醫藥 ; 乳癌 ; 荷爾蒙療法 ; 關節疼痛 ; 副作用 ; Traditional Chinese Medicine ; Breast cancer ; Hormone Therapy ; Arthralgia ; Side effects

期刊名称

中醫婦科醫學雜誌

卷期/出版年月

29卷2期(2022 / 12 / 01)

页次

65 - 72

内容语文

繁體中文

中文摘要

本文探討一位罹患乳癌的44歲女性,進行左側部分乳房切除及淋巴廓清術後,接受化療、放射線及荷爾蒙藥物治療,自從接受Tamoxifen(泰莫西芬)及Letrozole(復乳納)藥物治療後,即出現四肢、髖關節疼痛、僵硬,且潮熱、盜汗情形加劇。證屬肝腎陰虛、氣鬱化火、脾失健運、痰阻經絡,採用滋陰降火、健脾理氣化痰、舒經通絡的藥物,治療兩周後症狀獲得改善。由本病例發現若因荷爾蒙藥物導致關節疼痛問題,中藥使用上應注意陰虛、氣鬱化火、痰濕的癥候。適當使用滋陰降火、健脾理氣豁痰、舒經通絡藥物,可達到治療效果,並促進乳癌患者的生活品質。

英文摘要

A 44-year-old woman with breast cancer underwent partial mastectomy and left axillary lymph node dissection followed by chemotherapy, target therapy and hormone therapy. During the course of Tamoxifen and Letrozole, arthralgia and frequently hot flushes was noted. These symptoms belong to Yi deficiency of liver and kidney, liver stagnation which caused by emotional stress, spleen qi transportation was suppressed, stagnation of phlegm-dampness. The treatment was primarily based on nourishing yin, dispersing stagnated liver qi , regulating spleen qi, and relieving phlegm and dampness. After Chinese Medicine treatment, her discomfort and quality of life have been significantly improved.

主题分类 醫藥衛生 > 中醫藥學
参考文献
  1. 李耘瑄,張炯宏(2020)。中醫治療乳癌放療與荷爾蒙療法副作用之病例報告。中醫婦科醫學雜誌,25,44-52。
    連結:
  2. 陳安履,陳朝宗(2017)。中醫治療乳癌賀爾蒙療法副作用之病例報告。中醫內科醫學雜誌,15(1),70-82。
    連結:
  3. Chino, A,Okamoto, H,Hirasaki, Y,Ueda, K,Ogawa, K,Namiki, T(2011).A case of aromatase inhibitor (anastrozole)-induced side-effects successfully treated with Kampo medicines.J Altern Complement Med,17(11),1075-1077.
  4. Franzoi, MA,Agostinetto, E,Perachino, M,Del Mastro, L,de Azambuja, E,Vaz-Luis, I,Partridge, AH,Lambertini, M(2021).Evidence-based approaches for the management of side-effects of adjuvant endocrine therapy in patients with breast cancer.Lancet Oncol,22(7),e303-e313.
  5. Geisler, J(2011).Differences between the non-steroidal aromatase inhibitors anastrozole and Letrozole--of clinical importance?.Br J Cancer,104(7),1059-1066.
  6. Poo, CL,Dewadas, HD,Ng, FL,Foo, CN,Lim, YM(2021).Effect of Traditional Chinese Medicine on Musculoskeletal Symptoms in Breast Cancer: A Systematic Review and Meta-Analysis.J Pain Symptom Manage,62(1),159-173.
  7. 中華民國 108 年癌症登記報告。衛生福利部國民健康署編印,2022:3、71。