【論文摘要】The Effects of Helmet Ventilation During Walking Test in Patients with Stable Chronic Obstructive Pulmonary Disease: A Pilot Study

【論文摘要】頭盔式通氣於慢性阻塞性肺病行走運動測試的效益

10.6269/JRT.202107_20(2).0023

趙克耘(Ke-Yun Chao)；曾淇瑋(Chi-Wei Tseng)；劉偉倫(Wei-Lun Liu)；王鐘賢(Jong-Shyan Wang)

Chronic obstructive pulmonary disease ； helmet ventilation ； pulmonary rehabilitation ； six-minute walking test

呼吸治療

20卷2期（2021 / 07 / 01）

81 - 82

英文

Introduction: Symptoms of Chronic obstructive pulmonary disease (COPD) may contribute to activity restriction, deconditioning, and exercise intolerance. Non-invasive positive pressure ventilation (NIPPV) has been shown to improve exercise intolerance and health-related quality of life in patients with severe COPD. NIPPV can be applied during exercise training resulting in improved symptoms and increases the walking distance. However, the use of NIPPV as an adjunct to exercise programs is difficult and labour-intensive especially in patients who had never experienced NIPPV or intolerance to (of) the interface and positive pressure. Helmet is a new interface for NIPPV, an alternative to nasal or facemask. The previous report has been demonstrated the feasibility and benefits of helmet ventilation (HV) on critically ill patients with acute respiratory distress syndrome. Therefore, the present study aimed to determine whether HV on a 6-minute walk test (6MWT) would change the self-paced exercise performance and cardiopulmonary outcomes. Methods: We conducted a single site, prospective, randomized, crossover trial in the pulmonary rehabilitation unit. Patients with COPD who were confirmed by pulmonary function test were enrolled into this study. Acute exacerbation of COPD within 3 months, diagnosed neuromuscular disease, and unable to perform 6-MWT were excluded from this study. Results: A total of 20 participants were enrolled in this study. The mean difference in meters walked between the HV-aided and unaided walking scenarios was 15.4 ±37.2 (95% CI: -2.03 to 32.8, p =.145). The energy expenditure index showed no significant difference between HV-aided walking and unaided walking (median: 1.79 beats/meter walked vs. median: 1.67 beats/meter walked, p =.433). Heart rate (p =.002) and respiratory rate (p =.004) were significantly higher in HV-aided walking compared to the un-aided walking scenarios. Conclusion: The 6-minute walking distance did not increase in helmet ventilation-aided walking. The physiological parameters including heart rate and respiratory rate were favorable to unaided walking. The application of Helmet ventilation in self-paced exercise warrants further research with long-term follow-up.