上顎類基底鱗狀細胞癌－病例報告

Basaloid Squamous Cell Carcinoma over the Maxilla: A Case Report and Review of Literature

10.7104/TJOMS.200812.0293

鄭育誠(Yu-Chen Chen)；羅金文(Jin-Wun Luo)；林冠州(Kuan-Chou Lin)

類基底鱗狀細胞癌 ； 上顎 ； 硬顎 ； Basaloid squamous cell carcinoma ； Maxilla ； Palate

臺灣口腔顎面外科學會雜誌

19卷4期（2008 / 12 / 01）

293 - 301

繁體中文

類基底鱗狀細胞癌(Basaioid squamous cell carcinoma, BSCC)爲一種罕見高度惡性腫瘤，是鱗狀細胞癌(Squamous cell carcinoma, SCC)的一種變異。它好犯於頭頸部，主要是在喉部，下咽部，及舌基部。此種病患的存活率低，平均存活月數也只有20.8個月左右，且有高轉移率，大約50%的患者都有轉移的現象。它的臨床表徵和一般的鱗狀細胞癌並沒有太大的差別，組織學上和腺囊樣癌(Adenocystic carcinoma, ACC)，黏液上皮樣癌(Mucoepidermoid carcinoma)亦難以區分，故在初期做鑑別診斷時有其困難性。本篇文章提出一例上顎類基底鱗狀細胞癌之病例報告，並對其臨床上及病理上的表現、診斷、治療做一描述及文獻回顧。

Basaloid squamous cell carcinoma (BSCC) is an uncommon, high-grade biomorphic variant of squamous cell carcinoma (SCC) with a predilection for the head and neck regions. The majority of cases of BSCC occur in the supraglottic larynx, hypopharynx, tonsil and base of the tongue. Compared to typical squamous cell carcinoma, the survival rate of this kind of patient was low, the average survival period was only 20.8 months. Almost 5000 of the patients presented regional or distant metastases. Its symptoms and signs are similar to the traditional SCC. Microscopically, BSCC is very difficult to make a differential diagnosis between adenocystic carcinoma (ACC) and mucoepidermoid carcinoma. It will be difficult to diagnose BSCC if the specimen is too small. The clinical manifestations and treatment of this unusual lesion are presented, and the relevant literature is reviewed.