利用計算流體力學模擬肺動脈壓力來分析與肺動脈高壓症狀之間的關係

周孟瑾

doi:10.6342/NTU201600330

山西大学，您好！

感谢采购，人社期刊库｜人社论文库，期间：2025/01/01~2025/12/31

感谢试用，科学期刊库｜科学论文库，期间：2025/01/21~2025/03/31

浏览高级检索

关闭
检索检索高级检索出版物检索
浏览期刊主题浏览核心期刊浏览期刊拼音浏览

关闭

查询符号(半角)	查询符号意义说明
空格	表示为「AND」两个查询词之交集
双引号 ( " " )	片语以双引号标示开始及结束，而且只寻找出现顺序相同的字词，例： " image process "
?	表示一个字母切截，输入两个?表两个字母，依此类推，例：输入「Appl?」，查得结果应为appl e , appl y … ( 常用于英文字查询 )
*	表示不限字母切截，由0~n. 例：输入「appl*」，查得结果应为appl e , appl es , appl y , appl ied , appl ication … ( 常用于英文字查询 )
AND、OR、NOT	布尔逻辑组合关键字，用来扩大或缩小查询范围的技巧。 (1) AND ：缩小查询范围 (2) OR ：扩大查询范围(3) NOT：排除不相关的范围

DOI 是数位物件识别码（ D igital O bject I dentifier ）的简称，
为物件在网路上的唯一识别码，可用于永久连结并引用目标物件。

使用DOI作为永久连结

每个DOI号前面加上「 http://dx.doi.org/ 」便成为永久网址。
如以DOI号为 10.5297/ser.1201.002 的文献为例，此文献的永久连结便是： http://dx.doi.org/ 10.5297/ser.1201.002 。
日后不论出版单位如何更动此文献位置，永久连结所指向的位置皆会即时更新，不再错失重要的研究。

引用含有DOI的文献

有DOI的文献在引用时皆应同时引用DOI。若使用APA、Chicago以外未规范DOI的引用格式，可引用DOI永久连结。

DOI可强化引用精确性、增强学术圈连结，并给予使用者跨平台的良好使用经验，目前在全世界已有超过五千万个对象申请DOI。如想对DOI的使用与概念有进一步了解，请参考（）。

书目管理工具

相关连结

问题回报

全文下载

利用计算流体力学模拟肺动脉压力来分析与肺动脉高压症状之间的关系

Pulmonary artery pressure analysis on CT angiography using computational fluid dynamics simulation in patients with pulmonary hypertension

周孟瑾 , 硕士　　导师：张瑞峰　　

英文 DOI： 10.6342/NTU201600330

肺动脉；肺动脉高压；胸腔电脑断层扫描；计算流体力学； pulmonary artery ； pulmonary hypertension ； CT ； CFD

0 个人觉得这篇文章赞

摘要 │ 参考文献 (30) │ 国际计量

摘要〈TOP〉

并列摘要〈TOP〉

Pulmonary hypertension (PH) is a serious lung disease nowadays. Because the pulmonary artery (PA) structure is changed, resulting in the increase of PA blood pressure. Patients suffering from PH are difficult in breathing and fell chest pain. In clinic, several examinations, such as echocardiograph and computed tomography (CT) are used to examine the PH patient, and right heart catheterization is used to measure the PA blood pressure for PH diagnosis. Although these examinations are standard medical procedures, patients would not be diagnosed easily without obvious symptoms. In this study, we analyzed the PA pressure distribution on a three-dimensional (3-D) PA model built from a CT scan by using a computational fluid dynamics (CFD) software. The aim of this study is to offer a PH prediction model based on the pressure-based features extracted from the PA pressure distribution by the CFD simulation, and to increase the PH prediction accuracy. First, a semi-automatic segmentation was presented to obtain a 3-D PA model from a CT scan. After setting inlet and outlet planes on the 3-D PA model, the CFD simulation was performed to simulate the blood pressure distribution. Then, the pressure-based and volume-based features were used to extract the characteristics of the simulated PA pressure distribution and the PA structure, respectively. The experimental results showed that the PH prediction accuracy can be improved by using the pressure-based features. Originally, the PH prediction accuracy was 77.78% by using the combination of two volume-based pressures. Then, the accuracy was increase to 83.33% by using the combination of four pressure-based features and two volume-based features. Finally, the feature selection was used to select an optimal feature combination to obtain the highest accuracy of 88.89%.

参考文献 ( 30 ) 〈TOP〉

[2] C. J. Lettieri, S. D. Nathan, S. D. Barnett, S. Ahmad, and A. F. Shorr, "Prevalence and outcomes of pulmonary arterial hypertension in advanced idiopathic pulmonary fibrosis," CHEST Journal, vol. 129, pp. 746-752, 2006.
连结：
[3] L. M. Brown, H. Chen, S. Halpern, D. Taichman, M. D. McGoon, H. W. Farber, et al., "Delay in recognition of pulmonary arterial hypertension: factors identified from the REVEAL Registry," CHEST Journal, vol. 140, pp. 19-26, 2011.
连结：
[4] H. Nunes, M. Humbert, F. Capron, M. Brauner, O. Sitbon, J.-P. Battesti, et al., "Pulmonary hypertension associated with sarcoidosis: mechanisms, haemodynamics and prognosis," Thorax, vol. 61, pp. 68-74, 2006.
连结：
[6] J. Houtchens, D. Martin, and J. R. Klinger, "Diagnosis and management of pulmonary arterial hypertension," Pulmonary medicine, vol. 2011, 2011.
连结：
[7] A. Devaraj, A. U. Wells, M. G. Meister, T. J. Corte, and D. M. Hansell, "The Effect of Diffuse Pulmonary Fibrosis on the Reliability of CT Signs of Pulmonary Hypertension 1," Radiology, vol. 249, pp. 1042-1049, 2008.
连结：

国际计量

〈TOP〉

E-mail ：

文章公开取用时，将寄通知信至您填写的信箱地址

E-mail ：

使用DOI作为永久连结

引用含有DOI的文献

DOI可强化引用精确性、增强学术圈连结，并给予使用者跨平台的良好使用经验，目前在全世界已有超过五千万个对象申请DOI。 如想对DOI的使用与概念有进一步了解，请参考 （ ） 。

DOI可强化引用精确性、增强学术圈连结，并给予使用者跨平台的良好使用经验，目前在全世界已有超过五千万个对象申请DOI。如想对DOI的使用与概念有进一步了解，请参考（）。