臍帶自然乾燥對新生兒臍帶脫離時間成效－系統性文獻回顧暨統合分析

謝伶瑜; 陳碧惠

doi:10.6224/JN.202208_69(4).09

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P64 - 74

医药卫生 > 预防保健与卫生学
医药卫生 > 社会医学

DOI： 10.6224/JN

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脐带自然乾燥对新生儿脐带脱离时间成效－系统性文献回顾暨统合分析

The Effect of Dry Care on the Time of Umbilical Cord Separation in Newborns: A Systematic Review and Meta-Analysis

谢伶瑜(Ling-Yu HSIEH) ；陈碧惠(Pi-Hui CHEN)

护理杂志； 69 卷 4 期 (2022 / 08 / 01) ， P64 - 74

繁体中文 DOI： 10.6224/JN.202208_69(4).09

自然乾燥；脐带脱落时间；酒精； chlorhexidine ；母乳； dry care ； umbilical cord separation time ； alcohol ； chlorhexidine ； mother milk

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摘要 │ 参考文献 (29) │ 国际计量

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Background: There are many different approaches to umbilical cord care in clinical practice. Dry care is recommended by the WHO based on its ease of implementation and relatively low cost. However, the effect of dry care on the time of umbilical cord separation and related complications require further study. Purpose: The aim of this study was to conduct a systematic review and meta-analysis of randomized controlled trials to evaluate the effect of dry care on the time of umbilical cord separation and related adverse events in newborns. Methods: A literature search was conducted of articles published before December 2021 in the Cochrane Library, PubMed, Medline, CINAHL, Embase, Airiti Library, and National Digital Library of Theses in Taiwan databases. The research quality of the identified articles was assessed using the Modified Jadad Scale. Statistical analyses were performed using Review Manager, version 5.3, with statistics reported as mean differences with 95% confidence intervals. Results: Seven randomized controlled trials covering a total of 27,037 newborns were identified for analysis. Umbilical cord care in these studies included the following approaches: dry care, alcohol, chlorhexidine (CHX), mother's milk, and salicylic sugar powder (SSP). The results of the meta-analysis showed that umbilical cord separation time was significantly lower for the dry care approach compared to the alcohol approach (MD: -1.78 days, 95% CI: -2.4 to -1.16, three studies, n = 2,102) but not significantly different than the CHX approach (MD: -0.15 days, 95% CI [-1.99, 1.69], two studies, n = 10,519). Notably, the umbilical cord separation time for both mother's milk (MD: 1.19 days, 95% CI [0.82, 1.56], three studies, n = 730) and SSP (MD: 4.9 days, 95% CI [3.71, 6.09], one study, n = 92) approaches were reported as significantly less than the dry care approach. In addition, the CHX approach was associated with significantly fewer cord-related adverse events, while the alcohol, mother's milk, and SSP approaches were associated with rates of cord-related adverse advents similar to dry care. Conclusion / Implications for Practice: Because using dry care for umbilical cord care shortens the cord separation time compared to the alcohol approach and does not increase the incidence of omphalitis, this approach should be the first choice for cord care. Both mother's milk and SSP approaches are also associated with shorter umbilical cord separation times without adverse effects, and may be used as alternatives to dry care in umbilical cord care.

参考文献 ( 29 ) 〈TOP〉

庄其穆（2011）．临床医师如何阅读统合分析（Meta-analysis）的论文．台湾医界，54（2），74–82。[Chuang, C.-M. (2011). How clinicians read meta-analysis. Taiwan Medical Journal, 54(2), 74–82.] https://doi.org/10.30044/TMJ.201102.0003
连结：
刘美芳、李慈音（2009）．新生儿脐带护理的迷思．护理杂志，56（5），80–86。[Liu, M.-F., & Lee, T.-Y. (2009). Myth of neonatal umbilical cord care. The Journal of Nursing, 56(5), 80–86.] https://doi.org/10.6224/JN.56.5.80
连结：
Abbaszadeh, F., Hajizadeh, Z., & Jahangiri, M. (2016). Comparing the impact of topical application of human milk and chlorhexidine on cord separation time in newborns. Pakistan Journal of Medical Sciences, 32(1), 239–243. https://doi.org/10.12669/pjms.321.8223
连结：
Allam, N. A., AL Megrin, W. A., & Talat, A. M. (2015). The effect of topical application of mother milk on separation of umbilical cord for newborn babies. American Journal of Nursing Science, 4(5), 288–296. https://doi.org/10.11648/j.ajns.20150405.16
连结：
Al-Shehri, H. (2019). The use of alcohol versus dry care for the umbilical cord in newborns: A systematic review and meta-analysis of randomized and non-randomized studies. Cureus, 11(7), Article e5103. https://doi.org/10.7759/cureus.5103
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