Pulmonary Hypertension in Hemodialysis Patients Following Repeated Endovascular Thrombectomy

10.6515/ACS20150511C

Mu-Yang Hsieh；Lin Lin；Tsung-Yan Chen；Ren-Huei Wang；Su-Chin Huang；HsiuChiao Liu；Chao-Lun Lai；Shih-Yen Pu；Kuei-Chin Tsai；Chih-Cheng Wu

Graft ； Hemodialysis ； Pulmonary hypertension ； Thrombectomy ； Thrombosis

Acta Cardiologica Sinica

32卷3期（2016 / 05 / 01）

299 - 306

英文

Background: The prevalence of pulmonary hypertension is unusually high in Taiwanese patients with end-stage renal disease. Thrombosis of hemodialysis grafts is common and pulmonary embolism has been reported after endovascular thrombectomy. The aim of this study was to evaluate the relationship between pulmonary hypertension and endovascular thrombectomy of hemodialysis grafts. Methods: One hundred and ten patients on hemodialysis via arteriovenous grafts were enrolled in our study. The mean pulmonary artery pressure (PAP) was measured by right heart catheterization. Clinical information was collected by review of medical records. Comorbid cardiopulmonary disease was evaluated by echocardiography and chest X-ray. The history of patient vascular access thrombosis was reviewed from database, hemodialysis records, and interviews with staff at hemodialysis centers. Results: Fifty-two participants (47%) had pulmonary hypertension diagnosed by right heart catheterization. There was no difference in the number of thrombectomy procedures between patients with and without pulmonary hypertension. Based on multivariate analysis, the number of prior endovascular thrombectomy procedures did not correlate with mean PAP (F-value = 1.10, p = 0.30) nor was it associated with pulmonary hypertension (odds ratio = 0.92, p = 0.17). Conclusions: Prior endovascular arteriovenous graft thrombectomies were not associated with pulmonary hypertension or increased mean PAP in end-stage renal disease patients on maintenance hemodialysis.

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