题名

非肥胖成人減重兩公斤後對胰島素敏感性之影響

并列篇名

Effects of Two Kilogram Weight Loss on Insulin Sensitivity in Non-Obese Adults

DOI

10.6127/JEPF.2012.15.01

作者

呂香珠(Hsiang-Chu Lu);陳麗文(Li-Wen Chen);沈秋宏(Chiu-Hung Shen);高文揚(Wen-Yang Kao);程一雄(I-Shiung Cheng);林峰樟(Fong-Chang Lin)

关键词

運動 ; 胰島素 ; 胰島素阻抗 ; exercise ; insulin ; insulin resistance

期刊名称

運動生理暨體能學報

卷期/出版年月

15輯(2012 / 12 / 01)

页次

1 - 6

内容语文

繁體中文

中文摘要

Purpose: To determine whether two kilogram body weight loss could improve whole body insulin sensitivity through exercise training and dietary control in non-obesity adults. Methods: Fifteen women subjects were recruited to complete weight loss project with exercise training and dietary control. All blood samples were collected for analysis in glucose, insulin, insulin sensitivity index and triglycerides before and after experiment period, respectively. Results: The insulin levels were shown significant decrease in two kilogram weight loss compared to prior to weight project (7.45 ± 0.65 mU/ l and 6.57 ± 0.47 mU/l, p < .05). Insulin sensitivity was significantly improved after finishing weight loss project (7.86 ± 0.29 and 8.40 ± 0.25, p < .05). Conclusions: Dietary control with exercise training simultaneous is a good method for weight loss in non-obese adults. Weight loss up to 3.58% of the original weight could significantly improve whole body insulin sensitivity.

英文摘要

Purpose: To determine whether two kilogram body weight loss could improve whole body insulin sensitivity through exercise training and dietary control in non-obesity adults. Methods: Fifteen women subjects were recruited to complete weight loss project with exercise training and dietary control. All blood samples were collected for analysis in glucose, insulin, insulin sensitivity index and triglycerides before and after experiment period, respectively. Results: The insulin levels were shown significant decrease in two kilogram weight loss compared to prior to weight project (7.45 ± 0.65 mU/ l and 6.57 ± 0.47 mU/l, p < .05). Insulin sensitivity was significantly improved after finishing weight loss project (7.86 ± 0.29 and 8.40 ± 0.25, p < .05). Conclusions: Dietary control with exercise training simultaneous is a good method for weight loss in non-obese adults. Weight loss up to 3.58% of the original weight could significantly improve whole body insulin sensitivity.

主题分类 醫藥衛生 > 預防保健與衛生學
醫藥衛生 > 社會醫學
社會科學 > 體育學
参考文献
  1. 行政院衛生署國民健康局(2004)。代謝症候群臨床診斷準則。資料引自https://www.mjclinic.com.tw/news_content.aspx?co=3
  2. Bruce, C. R.,Hawley, J. A.(2004).Improvements in insulin resistance with aerobic exercise training: A lipocentric approach.Medicine & Science in Sports & Exercise,36(7),1196-1201.
  3. Dandona, P.,Aljada, A.,Bandyopadhyay, A.(2004).Inflammation: The link between insulin resistance, obesity and diabetes.Trends in Immunology,25(1),4-7.
  4. Eckel, R. H.,Grundy, S. M.,Zimmet, P. Z.(2005).The metabolic syndrome.Lancet,365(9468),1415-1428.
  5. Esposito, K.,Giugliano, F.,Di Palo, C.,Giugliano, G.,Marfella, R.,D''Andrea, F.(2004).Effect of lifestyle changes on erectile dysfunction in obese men: A randomized controlled trial.Journal of American Medical Association,291(24),2978-2984.
  6. Ferguson, M. A.,Alderson, N. L.,Trost, S. G.,Essig, D. A.,Burke, J. R.,Durstine, J. L.(1998).Effects of four different single exercise sessions on lipids, lipoproteins, and lipoprotein lipase.Journal of Applied Physiology,85(3),1169-1174.
  7. Fernández-Real, J.,Gutierrez, C.,Ricart, W.,Casamitjana, R.,Fernández-Castañer, M.,Vendrell, J.(1997).The TNF-alpha gene Nco I polymorphism influences the relationship among insulin resistance, percent body fat, and increased serum leptin levels.Diabetes,46(9),1468-1472.
  8. Goodpaster, B. H.,Katsiaras, A.,Kelley, D. E.(2003).Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesity.Diabetes,52(9),2191-2197.
  9. Goodpaster, B. H.,Thaete, F.,Simoneau, J.,Kelley, D.(1997).Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat.Diabetes,46(10),1579-1585.
  10. Grundy, S. M.,Brewer, H. B., Jr.,Cleeman, J. I.,Smith, S. C., Jr.,Lenfant, C.,National Heart, Lung, andBlood Institute(2004).Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition.Arteriosclerosis, Thrombosis, and Vascular Biology,24(2),e13-e18.
  11. Hotamisligil, G. S.(1999).Mechanisms of TNF-alpha-induced insulin resistance.Experimental and Clinical Endocrinology and Diabetes,107(2),119-125.
  12. Itoh, K.,Imai, K.,Masuda, T.,Abe, S.,Tanaka, M.,Koga, R.(2002).Relationship between changes in serum leptin levels and blood pressure after weight loss.Hypertension Research,25(6),881-886.
  13. Kasuga, M.(2006).Insulin resistance and pancreatic β cell failure.Journal of Clinical Investigation,116(7),1756-1760.
  14. McAuley, K. A.,Williams, S. M.,Mann, J. I.,Walker, R. J.,Lewis-Barned, N. J.,Temple, L. A.(2001).Diagnosing insulin resistance in the general population.Diabetes Care,24(3),460-464.
  15. McFarlane, S. I.,Banerji, M.,Sowers, J. R.(2001).Insulin resistance and cardiovascular disease.Journal of Clinical Endocrinology and Metabolism,86(2),713-718.
  16. Menshikova, E. V.,Ritov, V. B.,Toledo, F. G.,Ferrell, R. E.,Goodpaster, B. H.,Kelley, D. E.(2005).Effects of weight loss and physical activity on skeletal muscle mitochondrial function in obesity.American Journal of Physiology-Endocrinology and Metabolism,288(4),E818-E825.
  17. Shoelson, S. E.,Lee, J.,Goldfine, A. B.(2006).Inflammation and insulin resistance.Journal of Clinical Investigation,116(7),1793-1801.
  18. Summerfield, L. M.(2001).Nutrition, exercise, and behavior: An integrated approach to weight management.Belmont, CA:Wadsworth.
  19. Uusitupa, M.,Lindi, V.,Louheranta, A.,Salopuro, T.,Lindström, J.,Tuomilehto, J.(2003).Long-term improvement in insulin sensitivity by changing lifestyles of people with impaired glucose tolerance: 4-year results from the Finnish Diabetes Prevention Study.Diabetes,52(10),2532-2538.
  20. Zimmet, P. Z.,Alberti, K. G.,Shaw, J. E.(2005).Mainstreaming the metabolic syndrome: A definitive definition.Medical Journal of Australia,183(4),175-176.
  21. 林瑞興(2002)。博士論文(博士論文)。台北市,國立台灣師範大學體育學系。
  22. 陳嬿如、黃麗卿(2005)。胰島素敏感性及抗性之測定方法。基層醫學,20(10),253-259。
  23. 簡盟月、吳英黛(2006)。胰島素阻抗與運動訓練的效果─細胞與分子層面之探討。物理治療,31(2),130-141。
被引用次数
  1. Lee, Shu-Fen,Chii, Jeng(2016).Efficacy of aerobic exercise program on anthropometric measurements and glucose metabolism in obese adolescents with impaired glucose tolerance: A randomized controlled trial.體育學報,49(3),263-272.